Project

General

Profile

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    <FIELD name="contactemail">elke.lammertyn@kuleuven.be</FIELD>
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    <FIELD name="dateofcollection">2018-03-09</FIELD>
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    <FIELD name="title">Translational approaches to disease modifying therapy of type 1 diabetes: an innovative approach
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        towards understanding and arresting type 1 diabetes – Sofia ref.: 115797
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    </FIELD>
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    <FIELD name="startdate">2015-11-01</FIELD>
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    <FIELD name="summary">Preclinical type 1 diabetes (T1D) research has made important advances in recent years, but
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        less progress has been made in translating findings from in vitro and animal models into effective clinical
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        interventions. INNODIA aims to achieve a breakthrough in the way in which we study T1D to enable us to move
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        closer towards prevention and cure of T1D. To this end, INNODIA joins together the leading European experts from
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        the fields of basic and clinical T1D research, four leading pharmaceutical companies with strong expertise in
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        the discovery and development of diabetes medicines and the two leading public organizations involved in T1D
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        research into one comprehensive collaborative consortium. The clinicians in INNODIA oversee T1D registries and
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        have access to large populations of children and adults with T1D and family members at increased risk of
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        developing the disease. The basic science researchers are experts in beta-cell pathophysiology, immunology,
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        biomarker discovery, bioinformatics, systems biology and clinical trial design. INNODIA will accelerate
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        understanding of T1D through coordinated studies of unique clinical samples and translation-oriented preclinical
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        models. This should deliver novel biomarkers and interventions for testing in appropriately designed trials, to
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        be developed in active collaboration with regulators and patients. INNODIA provides access to unique historical
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        biorepositories and will create the Clinical Sample Network, a clinical EU infrastructure to recruit T1D
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        subjects at diagnosis and at-risk relatives. These individuals will be deep-phenotyped and will provide
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        biosamples, allowing the establishment of a ‘living biobank’ of subjects consented for recall. They will be
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        characterized using standardized clinical, genetic and metabolic phenotyping procedures, including prospective,
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        longitudinal sample collection to facilitate novel biomarker discovery. Diverse biological samples (blood,
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        plasma, serum, urine, stools, etc.) will be collected at
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    <FIELD name="acronym">INNODIA</FIELD>
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    <FIELD name="callidentifier">H2020-JTI-IMI2-2014-01-two-stage</FIELD>
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        <ITEM>Translational approaches to disease modifying therapy of Type 1 Diabetes Mellitus
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            (T1DM)###ec:h2020topics@@@Horizon 2020
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    <FIELD name="fundedamount">17630000</FIELD>
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    <FIELD name="optional2">Translational approaches to disease modifying therapy of Type 1 Diabetes Mellitus (T1DM)
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    <FIELD name="optional1">IMI2-2014-01-01</FIELD>
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    <FIELD name="enddate">2022-10-31</FIELD>
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    <FIELD name="dateoftransformation">2019-11-19</FIELD>
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    <FIELD name="contactfullname">LAMMERTYN, Elke</FIELD>
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