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<datacite:publicationYear>2016</datacite:publicationYear> |
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<datacite:creatorName>Juan Yepes-Nuñez</datacite:creatorName> |
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<datacite:creator> |
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<datacite:creatorName>Shreyas Gandhi</datacite:creatorName> |
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<datacite:creator> |
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<datacite:creatorName>Kirsten Beyer</datacite:creatorName> |
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<datacite:creatorName>Wesley Burks</datacite:creatorName> |
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<datacite:creator> |
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<datacite:creatorName>Giorgio Canonica</datacite:creatorName> |
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<datacite:creator> |
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<datacite:creatorName>Motohiro Ebisawa</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Rose Kamenwa</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Bee Lee</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Haiqi Li</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Susan Prescott</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>John Riva</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Alessandro Fiocchi</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Lanny Rosenwasser</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Hugh Sampson</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Michael Spigler</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Luigi Terracciano</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Andrea Vereda</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Susan Waserman</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Holger Schünemann</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Jan Brożek</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Ruby Pawankar</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Carlos Cuello-Garcia</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Yuan Zhang</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Gian Morgano</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Kangmo Ahn</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Suleiman Al-Hammadi</datacite:creatorName> |
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</datacite:creator> |
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<datacite:creator> |
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<datacite:creatorName>Arnav Agarwal</datacite:creatorName> |
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<datacite:identifier identifierType="URL">http://dx.doi.org/10.6084/m9.figshare.c.3629063 |
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<datacite:alternateIdentifier alternateIdentifierType="doi">10.6084/m9.figshare.c.3629063 |
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<datacite:titles> |
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<datacite:title>World Allergy Organization-McMaster University Guidelines for Allergic Disease |
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Prevention (GLAD-P): Vitamin D |
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</datacite:title> |
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</datacite:titles> |
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<datacite:descriptions> |
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<datacite:description descriptionType="Abstract">Abstract Background The prevalence of allergic diseases |
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is approximately 10 % in infants whose parents and siblings do not have allergic diseases and 20–30 |
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% in those with an allergic first-degree relative. Vitamin D is involved in the regulation of the |
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immune system and it may play a role in the development, severity and course of asthma and other |
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allergic diseases. Objective The World Allergy Organization (WAO) convened a guideline panel to |
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develop evidence-based recommendations addressing the use of vitamin D in primary prevention of |
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allergic diseases. Methods Our WAO guideline panel identified the most relevant clinical questions |
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and performed a systematic review of randomized controlled trials and non-randomized studies (NRS), |
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specifically cohort and case-control studies, of vitamin D supplementation for the prevention of |
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allergic diseases. We also reviewed the evidence about values and preferences, and resource |
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requirements (up to January 2015, with an update on January 30, 2016). We followed the Grading of |
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Recommendations Assessment, Development and Evaluation (GRADE) approach to develop recommendations. |
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Results Having reviewed the currently available evidence, the WAO guideline panel found no support |
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for the hypothesis that vitamin D supplementation reduces the risk of developing allergic diseases |
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in children. The WAO guideline panel suggest not using vitamin D in pregnant women, breastfeeding |
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mothers, or healthy term infants as a means of preventing the development of allergic diseases. This |
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recommendation does not apply to those mothers and infants who have other indications for |
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prophylactic or therapeutic use of vitamin D. The panel’s recommendations are conditional and |
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supported by very low certainty evidence. Conclusions WAO recommendations about vitamin D |
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supplementation for the prevention of allergic diseases support parents, clinicians and other health |
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care professionals in their decisions whether or not to use vitamin D in preventing allergic |
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diseases in healthy, term infants. |
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</datacite:description> |
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<datacite:subjects> |
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<datacite:subject>Medicine</datacite:subject> |
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<datacite:subject>Biotechnology</datacite:subject> |
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<datacite:subject>39999 Chemical Sciences not elsewhere classified</datacite:subject> |
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<datacite:subject>Immunology</datacite:subject> |
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<datacite:subject>69999 Biological Sciences not elsewhere classified</datacite:subject> |
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<datacite:subject>Developmental Biology</datacite:subject> |
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<datacite:subject>Cancer</datacite:subject> |
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<datacite:subject>Science Policy</datacite:subject> |
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</datacite:subjects> |
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<datacite:dates> |
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<datacite:date dateType="Issued">2016-01-01</datacite:date> |
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